>> Monday
>> Tuesday
>> Wednesday
Monday 30 June 2025
08:30 - 09:30
Session 01: Keynote session
Monday 30 June 2025
08:30 - 09:30: Session 01: Keynote session:
Chris Barratt, United Kingdom
Kirstine Kirkegaard, Denmark
08:30 - 09:00
Human Reproduction Keynote lecture: Human ovarian aging is characterized by oxidative damage and mitochondrial dysfunction
Sebastiaan Mastenbroek, The Netherlands
09:00 - 09:30
Detecting scientific fraud
Jennifer Byrne, Australia
09:00 - 12:00
Practicing embryo transfer techniques using a virtual reality-based simulator
09:00 - 12:00: Practicing embryo transfer techniques using a virtual reality-based simulator:
09:00 - 09:05
Welcome- course overview
09:05 - 09:35
Current embryo transfer practice: standardizing the embryo transfer protocol
09:35 - 09:55
Embryo transfer: the role of the embryologist
09:55 - 10:15
Discussion/ Q&A
10:15 - 12:00
Hands-on simulator training
09:30 - 10:00
Coffee break
09:30 - 10:00: Coffee break:
10:00 - 11:30
Session 02: Non invasive prediction of aneuploidy - are we there yet?
10:00 - 11:30: Session 02: Non invasive prediction of aneuploidy - are we there yet?:
Chairperson to be announced
10:00 - 10:15
Non-invasive metabolic profile of embryo culture media for preimplantation genetic diagnosis of aneuploidy.
10:15 - 10:30
Multi-center, external validation of a novel artificial intelligence (AI) model that predicts blastocyst PGT-A results from mature oocytes
10:30 - 10:45
Advancement of a novel image-analysis artificial intelligence (AI) model to predict blastocyst ploidy development of mature oocytes
10:45 - 11:00
Timing matters: Morphokinetic trajectories of 11,915 embryos provide new insights for blastocyst ploidy prediction using time-lapse monitoring
Andreu Quintana-Vehi, Spain
11:00 - 11:15
The role of morphokinetic meta-variables and clinical data to improve aneuploidy prediction in a novel developed machine learning model
11:15 - 11:30
Evaluating embryo selection: the discord between chromosomal screening and morphology
Ibrahim Elkhatib, United Arab Emirates
10:00 - 11:30
Session 03: Novels ways to improve fertility outcomes
10:00 - 11:30: Session 03: Novels ways to improve fertility outcomes:
Chairperson to be announced
10:00 - 10:15
OvoVid Phase 2: Role of micronutrients and probiotics supplementation on reproductive outcomes in an oocyte donation program: multicentric, double-blind, randomized, controlled trial
10:15 - 10:30
Vitamin D supplementation prior to in vitro fertilization in patients with polycystic ovary syndrome: a multicentre randomised double-blind placebo-controlled clinical trial
10:30 - 10:45
A live imaging system to study the spatiotemporal control of ovulation
Tabea Lilian Marx, Germany
10:45 - 11:00
Artificial intelligence based ultrasound for antral follicle count and ovulation triggering in ART cycles
Carolina Formica Muntaner, Argentina
11:00 - 11:15
Intraovarian treatment with a specific combination of stem cell-secreted factors reactivates ovarian function in a premature ovarian insufficiency (POI) mouse model
11:15 - 11:30
Unraveling the interplay of gut microbiota, metabolic alterations, and endometrial senescence in polycystic ovary syndrome and its implications for adverse pregnancy outcomes
10:00 - 11:30
Session 04: Male factors for ART success and failure
10:00 - 11:30: Session 04: Male factors for ART success and failure:
Frank Tüttelmann, Germany
Chairperson to be announced
10:00 - 10:15
Advanced paternal age affects miscarriage and live birth outcomes following the first transfer in oocyte donation cycles.
Maria Cristina Guglielmo, Italy
10:15 - 10:30
Semen human papilloma virus and in vitro fertilization: Machine learning insights into infection prevalence and embryologic outcomes
10:30 - 10:45
Exploring the longitudinal legacy/contribution of the male body mass index from semen to neonates in ART treatment: A real-world observational cohort study in China
10:45 - 11:00
Obstetric outcomes in pregnancies following intracytoplasmic sperm injection (ICSI) depend on the source of the sperms and the severity of male-factor infertility
11:00 - 11:15
Novel male genetic variants associated with unexpected poor fertilization outcomes in ICSI with high-quality donor oocytes
Ruth Morales Sabater, Spain
11:15 - 11:30
Impact of an oral antioxidant supplement (Impryl®) in men on semen quality and pregnancy rates, results of a multicentre, randomised, triple-blind, placebo-controlled trial (SUMMER trial)
Wiep De Ligny, The Netherlands
10:00 - 11:30
Session 05: RCTs and basic research in implantation and early pregnancy
10:00 - 11:30: Session 05: RCTs and basic research in implantation and early pregnancy:
Henriette Svarre Nielsen, Denmark
Chairperson to be announced
10:00 - 10:15
Endometrial scratching in couples with unexplained subfertility and a good prognosis for natural conception: a randomized controlled trial (SCRaTCH-OFO, trial register NTR6687/NL6498)
Emma Preesman, The Netherlands
10:15 - 10:30
Hydroxychloroquine for prevention of recurrent miscarriage: results of BBQ study, a french multicentre randomised placebo-controlled trial
Elisabeth Pasquier, France
10:30 - 10:45
Double blind randomised controlled trial of doxycycline in women with recurrent miscarriage and chronic endometritis: The CERM Trial
Siobhan Quenby, United Kingdom
10:45 - 11:00
The impact of endometrial preparation on pregnancy loss in vitrified-thawed euploid blastocyst transfer cycles: A randomized controlled trial.
Caroline Roelens, Belgium
11:00 - 11:15
A randomised controlled trial on post-warming incubation and transfer with hyaluronic acid and prolactin before single vitrified-warmed blastocyst transfer
11:15 - 11:30
Modeling embryonic adhesion at cellular resolution within a microfluidic endometrium-on-a-chip platform.
Sofía Zaragozano Martínez, Spain
10:00 - 11:30
Session 06: Reproductive outcomes after fertility preservation
10:00 - 11:30: Session 06: Reproductive outcomes after fertility preservation:
Kirsten Louise Tryde Macklon, Denmark
10:00 - 10:15
Beyond the cancer: twenty-year analysis of fertility preservation (FP) outcomes in young women with cancer (YWC).
Maya Sharon-Weiner, Canada
10:15 - 10:30
Maternal and perinatal outcomes according to the type of hematological treatment among females who conceived after a childhood or adolescent acute leukemia
Blandine Courbière, France
10:30 - 10:45
Reproductive health after soft tissue (STS) and bone sarcoma (BS): outcome assessment in a two-centre case series
10:45 - 11:00
Evaluating the effectiveness of fertility preservation strategies: A systematic review and network meta-analysis
11:00 - 11:15
The italian multicenter study on oncofertility: pregnancy outcomes after oocyte thawing comparing different cancer types
11:15 - 11:30
Fertility preservation in adolescent and young adult transgender men
Sarah Hadj-Kaddour, France
10:00 - 11:30
Session 07: The hidden impact of environment and chemicals on fertility
10:00 - 11:30: Session 07: The hidden impact of environment and chemicals on fertility:
Chairperson to be announced
Chairperson to be announced
10:00 - 10:15
Mercury exposure and reproductive health: insights from 150 women of childbearing age
Maria Madalena Cabral, Portugal
10:15 - 10:30
Gaining insight into the chemical exposome of deep endometriosis using metabolomics
GErman Cano-Sancho, France
10:30 - 10:45
Prenatal exposure to parental smoking and infertility in sons and daughters: a cohort study
Mette Jørgensen Langergaard, Denmark
10:45 - 11:00
Infertile women's awareness, risk perceptions, experiences and protection strategies regarding endocrine disrupting chemicals: a qualitative study
Gökhan Doğukan Akarsu, Turkey
11:00 - 11:15
Sleep characteristics and ovarian reserve in women undergoing assisted reproductive technology
11:15 - 11:30
Early fragile X screening for fertility preservation: a cost-effective strategy to enhance reproductive outcomes
Michal Rosenberg Friedman, Israel
10:00 - 11:30
Session 08: Poster discussion session
10:00 - 11:30: Session 08: Poster discussion session:
11:45 - 12:45
Session 09: Debate: Should we transfer embryos derived from 0PN-1PN-3PN?
11:45 - 12:45: Session 09: Debate: Should we transfer embryos derived from 0PN-1PN-3PN?:
Chairperson to be announced
Ioannis Sfontouris, Greece
Ioannis Sfontouris, Greece
11:45 - 12:45
Session 10: Data reporting session
11:45 - 12:45: Session 10: Data reporting session:
Dimitra Christopikou, Greece
Chairperson to be announced
11:45 - 12:15
Data from the ESHRE PGT consortium - year 2023
Eftychia Dimitriadou, Belgium
11:45 - 12:45
Session 11: ASRM Exchange session: Challenging cases: clinical and laboratory perspectives
11:45 - 12:45: Session 11: ASRM Exchange session: Challenging cases: clinical and laboratory perspectives:
Elizabeth Ginsburg, U.S.A.
Robert E. Brannigan, U.S.A.
11:45 - 12:00
Thin endometrium: cause for concern?
Elizabeth Ginsburg, U.S.A.
12:05 - 12:20
Contemporary approach to difficult cases in male reproduction
Robert E. Brannigan, U.S.A.
12:25 - 12:40
Importing cryopreserved gametes and embryos into the laboratory – know your limits!
11:45 - 12:45
Session 12: Managing weight and nurturing life
11:45 - 12:45: Session 12: Managing weight and nurturing life:
Antonis Makrigiannakis, Greece
11:45 - 12:05
The impact of obesity on reproduction from menarche to menopause
Fionnuala M McAuliffe, Ireland
12:15 - 12:35
Obesity, implantation and early pregnancy - does GLP1 play a role?
David Westergaard, Denmark
11:45 - 12:45
Session 13: IRHEC session: International Reproductive Health Education Collaboration (IRHEC) – An update
11:45 - 12:45: Session 13: IRHEC session: International Reproductive Health Education Collaboration (IRHEC) – An update:
Joyce Harper, United Kingdom
Alexandra Carvalho, Portugal
11:45 - 12:00
Goals, achievements, and ongoing activities – IRHEC update
Maria Ekstrand Ragnar, Sweden
12:05 - 12:20
Reproductive health education: mission, accomplishments and challenges
12:25 - 12:40
Likes, links, and learning: navigating reproductive health education in the digital era
Bola Grace, United Kingdom
11:45 - 12:45
Session 14: Poster discussion session
11:45 - 12:45: Session 14: Poster discussion session:
13:00 - 14:00
Lunch break
13:00 - 14:00: Lunch break:
14:00 - 15:00
Session 15: Whole genome sequencing of human embryos: technical challanges and ethical dilemmas
14:00 - 15:00: Session 15: Whole genome sequencing of human embryos: technical challanges and ethical dilemmas:
Edith Coonen, The Netherlands
Chairperson to be announced
14:00 - 14:20
Analytical capability and clinical utility of WGS in PGT
14:30 - 14:50
Ethical and counseling considerations
14:00 - 15:00
Session 16: Debate: IVF planning in poor prognosis patients - cycle to cycle approach or multicycle approach is best?
14:00 - 15:00: Session 16: Debate: IVF planning in poor prognosis patients - cycle to cycle approach or multicycle approach is best?:
14:00 - 14:15
Cycle to cycle approach is best!
14:15 - 14:30
Multicycle approach is a valid option in poor prognosis patients?
14:00 - 15:00
Session 17: FSANZ and CFAS Exchange session
14:00 - 15:00: Session 17: FSANZ and CFAS Exchange session:
Christian Simon Ottolini, Italy
14:00 - 14:20
Assessing the ploidy status of atypically fertilised embryos – recovery of embryos for potential clinical use
Sharyn Stock-Myer, Australia
14:30 - 14:50
A large proportion of cycle failure is associated with an excessive inflammation response
Marc-André Sirard, Canada
14:00 - 15:00
Session 18: Surgery as a valuable tool in the era of ART
14:00 - 15:00: Session 18: Surgery as a valuable tool in the era of ART:
Chairperson to be announced
14:00 - 14:15
Comparisons in the diagnostic criteria for defining uterine septum and clinical implications
J. Ricardo Loret de Mola, U.S.A.
14:15 - 14:30
Does the correction of the cesarean section scar defect improve the outcomes of IVF/ICSI?-A Retrospective Observational Study
14:30 - 14:45
Long-term anatomical and functional outcomes following laparoscopic repair of severe cesarean scar defect
14:45 - 15:00
Gastrointestinal function outcomes of women undergoing nerve-vessel sparing segmental or full-thickness discoid resection for deep colorectal endometriosis
14:00 - 15:00
Session 19: Live journal club: Male infertility, life expectancy, and long-term health risks: what can sperm reveal about health?
14:00 - 15:00: Session 19: Live journal club: Male infertility, life expectancy, and long-term health risks: what can sperm reveal about health?:
Juanjo Fraire-Zamora, Spain
14:00 - 14:02
Welcome & paper intro
14:02 - 14:07
ESHRE Journal club introduction - Human reproduction EIC representative
Kirstine Kirkegaard, Denmark
14:07 - 14:14
Paper presentation
14:14 - 14:15
Introduction of experts and moderators
14:15 - 14:16
Introduction of experts and moderators
14:16 - 14:56
Main discussion
Robert John Aitken, Australia
Chris Barratt, United Kingdom
Pippa Sangster, United Kingdom
Mónica Vazquez-Levin, Argentina
14:56 - 15:00
Closing & takeaways
14:00 - 15:00
Session 20: Poster discussion session
14:00 - 15:00: Session 20: Poster discussion session:
15:15 - 16:30
Session 21: Mitochondria and genetics in embryo development
15:15 - 16:30: Session 21: Mitochondria and genetics in embryo development:
Chairperson to be announced
Chairperson to be announced
15:15 - 15:30
Mitochondrial DNA ‘reversal’ is common in children born following meiotic spindle transfer, potentially reducing the efficacy of mitochondrial replacement therapies
Munuse Savash, United Kingdom
15:30 - 15:45
Biallelic variants in DLGAP5 cause spindle assembly defects and human early embryonic arrest
15:45 - 16:00
Mitochondrial replacement therapy effectively enhances embryo quality and pregnancy outcomes in patients with advanced maternal age and diminished ovarian reserve
Yaroslava Misyura, Ukraine
16:00 - 16:15
Mito-TALENs reduce mitochondrial DNA mutation load following pronuclear transfer
Noemi Castelluccio, Belgium
16:15 - 16:30
NAD+ precursor nicotinamide mononucleotide improves the developmental competence of bovine embryos through enhancement of mitochondrial function in morula
15:15 - 16:30
Session 22: New perspectives in non-obstructive azoospermia
15:15 - 16:30: Session 22: New perspectives in non-obstructive azoospermia:
Chairperson to be announced
15:15 - 15:30
A non-invasive multi-omics panel on cell free seminal plasma to predict the success of testicular sperm retrieval
15:30 - 15:45
Single-cell transcriptomic analysis of the immune-mediated component in Sertoli cell-only testes from patients with non-obstructive azoospermia
Andrea Guzmán-Jiménez, Spain
15:45 - 16:00
The DNA damage-sensing cGAS-STING pathway is critical in specific Telomere Variant Sequence synthesis in men with nonobstructive azoospermia and individuals with Differences of Sex Development
16:00 - 16:15
ASZ1-orchestrated dual epigenetic mechanisms underpinning meiotic fidelity
16:15 - 16:30
Prevalence and characteristics of idiopathic non-obstructive azoospermia according to the APHRODITE criteria: implications for hormonal optimization therapy.
15:15 - 16:30
Session 23: Novel biomarkers in implantation and early pregnancy
15:15 - 16:30: Session 23: Novel biomarkers in implantation and early pregnancy:
Chairperson to be announced
15:15 - 15:30
Global clinical insights into cell-free DNA for the genetic analysis of pregnancy loss
Nuria Balaguer Cuenca, Spain
15:30 - 15:45
Novel findings of thyroid dysfunction in pregnancy loss – suggestions for screening and further research
15:45 - 16:00
CD138 expression in the endometrium associates with endometrial timing and inflammatory status but not microbiota composition: a translational analysis of the CERM trial
Joshua Odendaal, United Kingdom
16:00 - 16:15
In vitro human Implantation modelling reveals the role of lysophosphatidic acid and Rho-ROCK pathway in driving cell-in-cell mechanisms during the initial embryo-endometrial interactions during implantation
16:15 - 16:30
Liquid chromatography-mass spectrometry profiling of the urine metabolome in adverse early pregnancy outcomes
Christopher Hill, United Kingdom
15:15 - 16:30
Session 24: Endometriosis and endometrial disorders: basic science
15:15 - 16:30: Session 24: Endometriosis and endometrial disorders: basic science:
Chairperson to be announced
15:15 - 15:30
Serum metabolic profiling in endometriosis reveals a strong metabolic signature for peritoneal endometriosis
15:30 - 15:45
Discrepancies between vaginal and endometrial microbiomes in IVF patients: implications for reproductive success
Diana Campos Rodero, Spain
15:45 - 16:00
Endometriosis induces DNA double-strand breaks and triggers apoptosis in oocytes of primordial follicles and its inhibition by melatonin administration
16:00 - 16:15
Construction of human endometrial complex organoids and their application in endometrial injury repair and regeneration
16:15 - 16:30
Spatio-temporal transcriptome of the human proliferative endometrium at a single-cell scale
Caroline Frisendahl, Sweden
15:15 - 16:30
Session 25: New era in reproductive genetic testing
15:15 - 16:30: Session 25: New era in reproductive genetic testing:
Chairperson to be announced
15:15 - 15:30
Survival of the fittest: unravelling aneuploid cell depletion in mosaic embryos
15:30 - 15:45
Optimizing Carrier Screening Panels: Integrating 8989 Internal Exomes, gnomAD v4.1, and Advanced Annotation Tools for Evidence-Based, Peer-Reviewed gene panel design
María Berbel Fernández, Spain
15:45 - 16:00
Whole transcriptome and genome sequencing of standard embryo biopsies can potentially reduce failed euploid transfers
16:15 - 16:30
Advancing embryo selection: combined DNA and RNA analysis in PGT
15:15 - 16:30
Session 26: Fine-tuning ART: small details, big impacts
15:15 - 16:30: Session 26: Fine-tuning ART: small details, big impacts:
Chairperson to be announced
15:15 - 15:30
How many is too many? Association between the number of laser shots applied during trophectoderm biopsy with DNA amplification and PGT cycles’ outcomes.
15:30 - 15:45
High-viscosity mineral oils provide enhanced protection to embryo culture systems against volatile organic compounds-induced embryotoxicity
Queralt Matia Algué, Spain
15:45 - 16:00
Validity of toxicity tests from certified consumables for sperm processing in IUI
16:00 - 16:15
Pregnancy complications in women with in-situ uterine fibroids compared to women without fibroids. From an American population database with almost 90,000 women with fibroids
16:15 - 16:30
Integrating 3D ultrasound uterine measurements and vascularity into Artificial Intelligence (AI) models to identify predictive features for assisted reproductive techniques.
15:15 - 16:30
Session 27: Poster discussion session
15:15 - 16:30: Session 27: Poster discussion session:
16:30 - 17:00
Coffee break
16:30 - 17:00: Coffee break:
17:00 - 18:00
Session 28: Diagnostics/screening tests for endometriosis
17:00 - 18:00: Session 28: Diagnostics/screening tests for endometriosis:
Chairperson to be announced
17:00 - 17:20
Imaging for endometriosis: from the past to the future
Mee Kristine Aas-Eng, Norway
17:30 - 17:50
Beyond imaging: are we there yet?
17:00 - 18:00
Session 29: Male infertility and comorbidities - what do we know?
17:00 - 18:00: Session 29: Male infertility and comorbidities - what do we know?:
Chairperson to be announced
Chairperson to be announced
17:00 - 17:20
What we know from big cohort studies
Michael Eisenberg, U.S.A.
17:30 - 17:50
What we know of putative causal relations
17:00 - 18:00
Session 30: Innovations in vitro gametogenesis and gonadogenesis
17:00 - 18:00: Session 30: Innovations in vitro gametogenesis and gonadogenesis:
Chairperson to be announced
Chairperson to be announced
17:00 - 17:20
Pioneering in vitro gametogenesis
17:30 - 17:50
Pluripotent models for gonadal research
Anna Biason-Lauber, Switzerland
17:00 - 18:00
Session 31: Challenging the dogmas of fertilisation
17:00 - 18:00: Session 31: Challenging the dogmas of fertilisation:
Chairperson to be announced
17:00 - 17:15
The utility of human two plus one small pronucleated zygotes (2.1pn) based on clinical outcomes and novel ploidy analysis
17:15 - 17:30
Incidence, development and ploidy of abnormally fertilized oocyte: implications for clinical practice
17:30 - 17:45
Determining the pre- and post-fertilization origins of aneuploidies: a new paradigm in assisted reproduction to substantially enhance embryo selection
Rick Essers, The Netherlands
17:45 - 18:00
Reconsidering the clinical value of 1PN-derived embryos: a systematic review and meta-analysis.
Beatrice Maria Barbagallo, Italy
17:00 - 18:00
Session 32: Guidelines session:Key updates on the ESHRE guidelines
17:00 - 18:00: Session 32: Guidelines session:Key updates on the ESHRE guidelines:
Chairperson to be announced
17:00 - 17:20
Good practice recommendations on fertility preservation in child and adolescent males receiving gonadotoxic therapies
Rod Mitchell, United Kingdom
17:30 - 17:50
A revised ESHRE/ALPHA consensus on oocyte and embryo assessment: 5 essential takeaways
Giovanni Coticchio, Italy
17:00 - 18:00
Session 33: Poster discussion session
17:00 - 18:00: Session 33: Poster discussion session: