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PERINATAL OUTCOME
Neonatal outcome in ART vs SC
Meta analysis ART compared to SC: higher risk in ART
• 1.5-2x
• 2x
• 3x
• 2x
• 30%
Prematurity
Low birthweight Very low birthweight Perinatal mortality
More congenital malformations
2.5% general population  3.5% ART
Helmerhorst et al., 2004; Jackson et al., 2004; McGovern et al., 2004;
McDonald et al., 2009; Henningsen et al., 2014; Marino et al., 2014; Qin et al., 2017; Hoorsan 2017
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PERINATAL OUTCOME
Literature data CoNARTaS studies
ART compared to SC: higher risk due to
• Prematurity
• Birthweight
• Perinatal mortality
• Malformations
• Macrosomies
higher < to maternal factor and ART
lower < to maternal factor and ART higher < more placental praevia in ART higher < gastro-intestinal cardio-vascular,
uro-genital higher < cryopreservation
Henningsen et al. Acta Obstet Gynecol Scand. 2018
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