Page 140 - ESHRE2019

HEALTH OF ICSI CHILDREN
Content
Introduction
Perinatal outcome and congenital malformation
Long-term medical outcome Neuro-developmental and psychological outcome Epigenetics and cancer
Reproductive health
Conclusion
ESHRE 2019
26-5-2019 | 11
PERINATAL OUTCOME
Prenatal tests in ICSI
Bonduelle (2002)
% in reference population
p
Jozwiak (2004)
Number of foetusses
1586
1136
Karyotype anomalies
47
17
De novo: autosomes + sex
1.6%
15 +10
0.45-0.87%
<0.001
1.2% 7 +7
Inherited
1.4%
22
0.47%
<0.001
0.3% 3
TOTAL (95%CI)
2.96% (2.19‐3.92)
1.50% (0.87‐2.39)
Bonduelle et al. Human Reprod. 2002, 17 (10): 2600-2614
ESHRE 2019
26-5-2019 | 12
138
134