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Cumulative live birth rate after miscarriage in first cycle of IVF
• UK population‐based cohort study of 112,549 women who started their first IVF treatment between 1999 and 2008 (Cameron et al, 2017)
• Human Fertilisation and Embryology Authority (HFEA) register
• Cumulative live birth rates (CLBR) estimated in women who had:
1. Miscarriage (and no live birth);
2. At least one live birth;
3. No pregnancy
in their first complete cycle of IVF/ICSI
• Complete cycle – fresh and frozen embryo transfers following a single oocyte retrieval episode
Characteristics of women entering their second complete cycle by outcome of first complete cycle
CHARACTERISTIC
OUTCOME OF FIRST CYCLE,
n (%) unless otherwise stated
NO PREGNANCY
MISCARRIAGE
LIVE BIRTH
n (%)
39413 (79.9)
5369 (10.9)
3931 (8.0)
Age (year), mean (SD)
35 (4.4)
35 (4.2)
35 (3.9)
Duration of infertility, median(IQR)
5 (3‐7)
4 (3‐7)
6 (4‐8)
Primary infertility
28965 (73.5)
3665 (74.0)
2737 (78.7)
Cause of infertility
>1 cause
5845 (14.8)
791 (14.7)
605 (15.4)
Tubal
6544 (16.6)
874 (16.3)
564 (14.3)
Anovulatory
2547 (6.5)
355 (6.6)
224 (5.7)
Male factor
13175 (33.4)
1858 (34.6)
1627 (41.4)
Endometriosis
1393 (3.5)
154 (2.9)
108 (2.7)
Unexplained
9737 (24.7)
1316 (24.5)
782 (19.9)
Cameron et al, 2017
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PRECONGRESS COURSE 06 I VIENNA, AUSTRIA – 23 JUNE 2019 13