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When to treat thrombotic APS?
Two positive aPL MR direct thrombus imaging in comparison to 12 weeks apart venography in imaging DVT
&
a thrombotic event proven by imaging
Management of thrombosis in APS
• Ourolddata(1995)-70%riskofrecurrent thrombosis - but tertiary centre seeing v worse cases
• Long-term oral anticoagulation target INR of 3-4 especially arterial or microvascular disease
• New Engl J Med 1995; 332: 993-7
• Regular follow-up
• Vigorously treat atherogenic risk factors
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PRECONGRESS COURSE 06 I VIENNA, AUSTRIA – 23 JUNE 2019 109
