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NON PATHOGENIC ANTIPHOSPHOLIPID ANTIBODIES
(ANTI-B2GPI NEGATIVE)
Drugs
Procainamide, hydralazine, beta blockers Quinine
Phenothiazines, phenytoin
Alpha interferon
Infectious disease
Syphilis, Lyme disease
Tuberculosis
Bacterial endocarditis Mycoplasma pneumonia HIV
Hepatitis A/B/C virus B19 parvovirus
Predicting risk of thrombosis in APS
• Lupus anticoagulant higher risk of thrombosis than ACA (Galli 2002)
• High titre ACA > risk than low titre ACA
• Triple positivity > double > single (LA/ACA/antibeta2GPI) (Pengo 2010)
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