Page 58 - ESHRE2019
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Sperm DNA Fragmentation is observed in several causes of male infertility
Heat :
Varicocele
(Blumer et al., 2012, Zini and Dohle, 2011)
Cryptorchidism, small scrotum, retractile testes, obesity
(Kort et al. 2006, Chavarro et al. 2010, Fariello et al. 2012, La Vignera et al. 2012, Dupont et al. 2013)
Tight underwear (Ahmad et al. 2012) Occupational exposure (bakers...)
Recreational exposure (hot baths, jaccuzzi, sauna, hammam...) (Garolla et al. 2013)
Intense sport (running, cycling, cardio-training...)
(Southorn 2002)
Laptop on the legs (Sheynkin et al. 2011,) Fever (Sergerie et al., 2007)
Sperm DNA Fragmentation is observed in several causes of male infertility
• Leukocytospermia, Genito-Urinary Infection/inflammation
(Alvarez et al., 2002; Erenpreiss et al., 2002; Fariello et al., 2009)
• General inflammatory diseases
• Cancer, radiotherapy, chemotherapy
• Life style: smoking (Elshal et al., 2009), alcohol, caffeine, deficient diet
• Environmental: pesticides, plastics, cadmium, lead...
(Rignell‐Hydbom et al., 2005; Sanchez‐Pena et al., 2004; Vani et al., 2012)
• Cell-phone in trouser pocket (Desai et al. 2009)
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