Page 17 - PCC02
P. 17
The Glucose story
30 25 20 15 10
5 0
123456 Days
• Glucose is needed during fertilization
• Zygotes and early embryos prefer pyruvate/lactate as energy source
– Glucose free medium?
• Glucose consumption increase from cleavage stages to blastocyst stage
Gott et al., 1990
40
35
30
25
20
15
10
5 0
EBSS+G EBSS‐G
Glucose free medium after fertilization?
Large Prospective clinical trial in Leeds – 741 cycles
Implantation rate
Pregnancy rate/ER
Birth rate/ER
Twins
Triplets
No significant differences
Coates et al., 1999
Page 11 of 151
PRECONGRESS COURSE 02 I BARCELONA, SPAIN – 1 JULY 2018 17
pmol/embryo/hour
