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Condition pairs
A–B
A–C
A–D
B–C
B–D
C–D
Microarray data analysis
Number of probe sets
2
900
2595
Up in A: 1
Down in A: 1
Up in A: 590
Down in A: 310
Up in A: 1347
785
2407
Down in A: 1248
Up in B: 495
Down in B: 290
Up in B: 1217
1228
Down in B: 1190
Up in C: 437
Down in C: 791
Conclusions
• Only slight difference between groups A and B
• A bolus of 1500 IU hCG normalizes the endometrial gene expression pattern after GnRHa trigger
(Humaidan et al., 2006; Humaidan et al., 2010)
• Genes involved of importance for implantation and endometrial receptivity (MMPs, interleukins, integrins)
(Macklon et al., 2008; Tabibzadeh, 2002; Van Vaerenbergh et al., 2011; Pilka et al., 2003; Lindhard et al., 2002; Ledee-Bataille et al., 2004 and 2005)
24
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PRECONGRESS COURSE 06 I GENEVA, SWITZERLAND – 2 JULY 2017 127
