Page 29 - PRECONGRESS COURSE 03
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Bivalents (mostly) biorientate by anaphase
40 30 20 10
043210 Hours before Anapase
Anaphase
Lane et al Development 2012
... in the 5% that don’t, bivalents undergo non‐disjunction
CenpC Histone2B
Lane et al Development 2012
Page 25 of 102
PRECONGRESS COURSE 03 I GENEVA, SWITZERLAND – 2 JULY 2017 29
Oocytes with non-aligned bivalents (%)


































































































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