Page 30 - PRECONGRESS COURSE 03

Non‐aligned bivalents do not slow down cyclin B1 degradation (=APC activity)
E
100 80 60 40 20
03579
Hours
4:10 4:20 4:30 4:40 4:50 5:00 5:10 5:20
5:30 5:40 5:50 6:00 6:10 6:20 6:30 6:40
6:50 7:00 7:10 7:20 7:30 7:40 7:50 8:00
Non‐aligned bivalents do not delay polar body extrusion
Histone2B
Lane et al Development 2012
AB
C
4:30 5:00 4:30 5:00
5:30 6:00 6:30 7:00 7:30 8:05 5:30 6:00 6:30 7:00 7:30 8:00
n.s.
10 (23) (18)
8 6 4 2 0
Lane et al Development 2012
yes no Alignment
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Anaphase (hours post NEB)
Cyclin B1-Venus (% of max)