Page 27 - PRECONGRESS COURSE 03
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APC activity required for anaphase
Cdc20
Cdk1
Separase
A
A
P
PC
C
ANAPHASE!
Active
• Cdc20 activates the APC
• Securin and Cyclin B1 are degraded
• Anaphase ensues
Meiosis I division is unique
Dyads
Kinetochores
Watanabe Nature Rev MCB (2012)
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PRECONGRESS COURSE 03 I GENEVA, SWITZERLAND – 2 JULY 2017 27
