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Sperm preparation
Evidence for the Use of One technique Compared to Another Treatment
• Very few RCT’s comparing treatment outcomes: IUI • Cochrane review
Semen preparation techniques for intrauterine insemination: no evidence Boomsma et al. Cochrane Database Syst Revs 2012; Issue 6.
ESHRE, 2017 Sperm preparation, Nijs M.
• •
Sperm prepration
Evidence for the Use of One technique Compared to Another Novel techniques
Selection based on sperm surface charge (electrophoresis – Zeta potential)
Non‐apoptotic sperm selection (annexin V Magnetic‐activated cell sorting)
Novel sperm selection methods show promising results. However, they have not yet established themselves in routine practice. Despite these encouraging results, it should be noted that the numbers of patients assessed are limited, and most studies are underpowered to conclude on differences in pregnancy rates and live births. More research is needed.
ESHRE, 2017 Sperm preparation, Nijs M.
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