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P-524 Genetics of infertility: Diagnostic interests of a custom designed panel for the analysis of 51 genes involved in non-syndromic human infertility
O. Okutman1,2, J. Tarabeux3, J. Muller3,4, S. Viville1,2
1Hôpitaux Universitaires de Strasbourg- Nouvel hôpital civil, Laboratoire de diagnostic génétique- UF3472 Infertilité, Strasbourg, France
2IPPTS, Université de Strasbourg, Strasbourg, France
3Laboratoire de Diagnostic Génétique, Hôpitaux Universitaires se Strasbourg, Strasbourg, France 4Laboratoire de Génétique Médicale, Universite de Strasbourg, Strasbourg, France
P-525 Thaw, biopsy and refreeze procedure for PGT-A analysis of previously cryopreserved embryos
M. Wilding1, M. Terribile1, I. Parisi1, G. Nargund1 1Create fertility, Embryology, London, United Kingdom
P-526 Impact of semen quality on blastocyst mosaicism in preimplantation genetic testing for aneuploidy
N. Tarozzi1, G. Coticchio1, M. Nadalini1, C. Lagalla1, A. Borini1 19.Baby, Family and Fertility Center, Bologna, Italy
P-527 To examine concordance and mosaicism in oocytes and embryos
K. Berrisford1, S. Fishel1, E. Armstrong2, L. Davies1, C. Miralles3 1CARE, Embryology, Nottingham, United Kingdom
2CARE, Embryology, Birmingham, United Kingdom
3CARE, Embryology, Northampton, United Kingdom
P-528 Pre-conceptional maternal exposure to cyclophosphamide results in modifications of DNA methylation in F1 and F2 mouse oocytes: evidence for transgenerational effects
M. D’Aurora1, G. Di Emidio2, S. Franchi1, M. Placidi2, G. Rossi2, L. Stuppia1, P.G. Artini3, C. Tatone2, V. Gatta1
1University of Chieti, Department of Psychological- Health and Territorial Sciences, Chieti, Italy 2University of L’Aquila, Department of Life- Health and Environmental Sciences, L’Aquila, Italy
3University of Pisa, Department of Clinical and Experimental Medicine- Division of Obstetrics and Gynecology Oncology, Pisa, Italy
P-529 Chromosomal aberrations and aneuploidy features in IVF blastocysts and abortion villus
X. Zhang1, Y. Wang1, N. Zhao1, P. Liu1, J. Huang1
1Peking University Third Hospital, Obstetrics and Gynecology, Beijing, China
P-530 Demystifying the effect of paternal age on blastocyst ploidy status
W. Saab1, S. Seshadri1, X. Vinals-Gonzalez2, R. Odia2, D. Cansfield2, J. Bennagi1, P. Serhal1, F. Steyn3, S. Cawood2, W. Saab4, C. Heath2
1Centre for Reproductive and Genetic Health, Clinicians, London, United Kingdom 2Centre for Reproductive and Genetic Health, Embryologist, London, United Kingdom 3Centre for Reproductive and Genetic Health, nursing, London, United Kingdom
4The Lebanese American University, Medical Student, Beirut, Lebanon
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