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 P-519 Clinical outcomes of comprehensive 24-chromosome preimplantation Genetic testing in couples with balanced reciprocal or Robertsonian translocations
L. Yang1,2, P. Xie2,3, L. Hu1,2,3,4, Y. Tan1,2,3,4, K. Luo1,2, F. Gong1,2,3,4, G. Lu1,2,3,4, G. Lin1,2,3,4 1Reproductive and Genetic Hospital of Citic-Xiangya, Reproductive Center, Changsha, China
2Key Laboratory of Stem Cells and Reproductive Engineering- Ministry of Health, Research and Development Department, Changsha, China
3National Engineering and Research Center of Human Stem Cell, Research and Development Department, Changsha, China
4Institute of Reproduction and Stem Cell Engineering- Central South University, Basic medicine, Changsha, China
P-520 Whole genome amplification (WGA) allowing combined PGT-A and PGT-M for detection of heteroplasmy and estimation of mtDNA mutation load in embryos
S. Anthony1, M. Jasper1
1Perkin Elmer Health Sciences Ltd, Perkin Elmer Health Sciences Ltd, Adelaide, Australia
P-521 Comparative proteomics of Seminal Exosomes reveal deregulation of cell signalling and defects in chromatin remodelling in Recurrent Pregnancy Loss Patients
S.R. Jena1, G. Mohanty1, J. Nayak1, S. Kar2, L. Samanta1
1Ravenshaw University, Department of Zoology, Cuttack, India
2Kar Clinic and Hospital Private Limited, Department of Obstetrics and Gynaecology, Bhubaneswar, India
P-522 TGFβ/SMAD signaling regulates transzonal projection (TZP) formation in growing follicles of the mouse ovary
S. Granados Aparici1, Q. Yang1, H. Clarke1
1Research Institute - McGill University Health Centre- McGill University, Obstetrics and Gynecology, Montreal, Canada
P-523 Paternal Age Has No Impact on Aneuploidy Rate in Embryos Derived from Young Egg Donors
D. Michal1,2, S. Madjunkova3, R. Antes3, R. Abramov3, S. Chen3, M. Albar2, A. Koziarz4, J. Mashiach1,2, S. Moskovtsev2,5, I. Kuznyetsova6, C. Librach2,7,8,9,10
1CReATe Fertility Centre, Research, Toronto, Canada
2University of Toronto, Department of Obstetrics and Gynecology, Toronto, Canada 3CReATe Fertility Centre, Reproductive genetics, Toronto, Canada
4University of Toronto, Faculty of Medicine, Toronto, Canada
5CReATe Fertility Centre, Department of Andrology, Toronto, Canada
6CReATe Fertility Centre, IVF laboratory, Toronto, Canada
7CReATe Fertility Centre, Clinic Director, Toronto, Canada
8University of Toronto, Institute of Medical Sciences, Toronto, Canada
9University of Toronto, Department of Physiology, Toronto, Canada
10Women’s College Hospital, Department of Gynecology, Toronto, Canada
                POSTERS I VIENNA, AUSTRIA – 23 TO 26 JUNE 2019 281
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