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Allocation concealment matters
Wood et al 2008
2. Allocation concealment
LOW RISK
• Central randomisation or telephone (e.g. telephone)
• Sequentially numbered, opaque, sealed envelopes (SNOSE)
• Sequentially numbered drug containers of identical appearance • Computer based randomisation linked to participant enrolment
UNCLEAR RISK
• No description of allocation concealment
• Stated as “concealed” only with no further description • Unclear if envelopes are all of SNOSE criteria
HIGH RISK
• Open allocation list
• Envelopes not all of SNOSE criteria
Edited from booklet
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