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Outline
Have mosaic embryos potential for implantation?
Should mosaic embryos be considered useful for transfer in IVF treatments?
May the extent of mosaicism and the type of aneuploidy involved affect the IVF success rate?
Chromosomal mosaicism Mosaicism: the presence of chromosomally distinct cell lines
within the same embryo
mosaic diploid/aneuploid: mixture of diploid and aneuploid cell lines
mosaic aneuploidy: mixture of cell lines with different chromosomal abnormalities
Chromosomal mosaicism is a relatively common finding in IVF- derived human embryos and may affect:
15–90% of cleavage stage embryos 30-40% of blastocysts
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