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Conclusions
• Mosaicism reportedly common during preimplantation phase
• Mosaic embryos sometimes produce viable pregnancies
• Outcomes for mosaic embryos poorer that those euploid after PGT-A • Implications for the use of PGT-A and patient counselling
• Rate of mosaicism appears to be influenced by clinic-specific factors • Biopsy technique does not affect rate of mosaic abnormalities
• Certain patient groups may generate more mosaic embryos
• Some guidelines/consensus statements (e.g. PGDIS, COGEN)
ACKNOWLEDGEMENTS
Zeynep Gunes Nada Kubikova Kishlay Kumar Megan Lever Columba Avila Perez Araz Raberi
Samer Alfarawati Dhruti Babariya Tishy Bruce Georgina Cutts Elpida Fragouli Ayman Haj Ali Katharina Spath
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