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Single Single chromsome loss chromsome gain
Complex
Segmental aneuploidies
Mosaic embryos
Mosaicism arise from mitotic errors occurring after fertilization (usually after the first three cleavage divisions)
The number of aneuploidy cells within mosaic embryos depend on the time at which the mitotic error occurs
Aneuploidy in mosaic embryos may be composed of different type of aneuploidies
Mitotic error
Aneuploid blastomere
Euploid blastomere
Zygote
Mitotic error
Cleavage
Morula
How to consider mosaic embryos?
Typically, mosaic embryos have not been considered useful for transfer in IVF treatment
Similarly to aneuploid embryos, they were considered abnormal
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Mosaicism level
PRECONGRESS COURSE 10 I VIENNA, AUSTRIA – 23 JUNE 2019 107
Mitotic error