Page 53 - ESHRE2019

Assessing for an “Endometrial Factor”
Curette: 3 mm outer diameter Inner Stylette: Cutting edge Syringe: Vacuum
Advantages:
 Column of endometrial tissue intact  No cervical contamination upon
removal
Cochrane Review, updated 2018
Haas DM, Hathaway TJ, Ramsey PS
• To assess the efficacy and safety of progestogens as a preventative therapy against recurrent miscarriage
• Randomized or quasi-randomized controlled trials; placebo or no treatment
• 13 trials with 2,556 women: 9 compared progestogen with placebo and 4 compared progestogen with no treatment
• Multicenter and single-center trials; Egypt, India, Jordan, UK and USA
• RPL: 6 trials ≥3 “miscarriages” and 7 trials ≥2 “miscarriages”
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