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  Retrospective study of hydroxychloroquine in our unit
      HCQ group N = 51
Control group N = 119
Live birth rate
66.7%
57.1%
p=0.05
Overall pregnancy morbidity
47.1%
63.0%
p=0.004
Fetal losses > 10 weeks
2%
10.9%
p=0.05
Ischemic placenta mediated complications
2%
10.9%
p=0.05
Pregnancy duration
27.6 [6‐40]
21.5 [6‐40]
p=0.03
Live births before 37 weeks
3.9%
13.4%
P=0.05
              Sciascia et al, AMOG, 2015
   HYPATIA study
• A prospective randomised controlled trial of HYdroxychoroquine versus placebo during Pregnancy in women with AnTIphospholipid Antibodies
• Objective: To study the effect of HCQ on pregnancy outcome in women with antiphospholipid antibodies.
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