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Reviews
Bibliography
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2. Harper JC, Aittomaki K, Borry P, Cornel MC, de Wert G, Dondorp et al. Recent developments in genetics and medically assisted reproduction:
from research to clinical applications. Eur. J. Hum. Genet. 26, 12-33 (2018).
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Primary Literature
1. Tokuhiro K and Dean J. Glycan-independent gamete recognition triggers egg zinc sparks and ZP2 cleavage to prevent polyspermy. Dev. Cell 46, 627-640 (2018).
2. Xiong B, Zhao Y, Beall S, Sadusky AB, Dean J. A unique egg cortical granule localization motif is required for ovastacin sequestration to prevent premature ZP2 cleavage and ensure female fertility in mice. PLoS Genet. 13, e1006580 (2017).
3. Que EL, Bleher R, Duncan FE, Kong BY, Gleber SC, Vogt S et al. Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks. Nat. Chem. 7, 13-139 (2015).
Bibliography
4. Avella MA, Baibakov B, Jimenez-Movilla M, Sadusky AB, Dean J. ZP2 peptide-beads select human sperm in vitro, decoy mouse sperm in vivo and provide reversible contraception. Sci. Transl. Med. 8, 336ra360 (2016).
5. Avella MA, Baibakov B, Dean J. A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans. J. Cell Biol. 205, 801-809 (2014).
6. Burkart AD, Xiong B, Baibakov B, Jimenez-Movilla M, Dean J. Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy. J. Cell Biol. 197, 37-44 (2012).
7. Baibakov B, Boggs NA, Yauger B, Baibakov G, Dean J. Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice. J. Cell Biol. 197, 897-905 (2012).
8. Gahlay G, Gauthier L, Baibakov B, Epifano O, Dean J. Gamete recognition in mice depends on the cleavage status of an egg's zona pellucida protein. Science 329, 216-219 (2010).
9. Quesada V, Sanchez LM, Alvarez J, Lopez-Otin C. Identification and characterization of human and mouse ovastacin: a novel metalloproteinase similar to hatching enzymes from arthropods, birds, amphibians and fish. J. Biol. Chem. 279, 266627-26634 (2004).
10. Bauskin AR, Franken DR, Eberspaecher U, Donner P. Characterization of human zona pellucida glycoproteins. Mol. Hum. Reprod. 5, 534-540 (1999).
11. Bleil JD, Deall CF, Wassarman PM. Mammalian sperm-egg interaction: fertilization of mouse eggs triggers modification of the major zona pellucida glycoprotein ZP2. Dev. Biol. 86, 189-197 (1981)
12. Bleil JD and Wassarman PM. Structure and function of the zona pellucida: identification and characterization of the proteins of the mouse oocyte’s zona pellucida. Dev. Biol. 76, 185-202 (1980).
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