Page 147 - ESHRE2019
P. 147
HEALTH OF ICSI CHILDREN
Content
Introduction
Perinatal outcome and congenital malformation Long-term medical outcome
Neuro-developmental and psychological outcome Epigenetics and cancer
Reproductive health
Conclusion
ESHRE 2019
26-5-2019 | 25
NEURO-DEVELOPMENT
Risk for neurological sequellae and cerebral palsy
Danish national register based cohort study, 1995-2000. Age 2-7 years ICSI: n=1149 singletons, 411 twins
IVF: n=3456 singletons, 1262 twins
ICSI vs IVF: not increased risk
AOR 0.9 (95% CI 0.5-1.6) Neurological sequelae (cerebral palsy, mental retardation, severe mental developmental disturbances and retarded psychomotor development)
AOR 0.8 (95% CI 0.3-2.4) Cerebral palsy
Pinborg et al. BMJ 2004 Aug 7;329(7461):311.
ESHRE 2019
26-5-2019 | 26
141
PRECONGRESS COURSE 01 I VIENNA, AUSTRIA – 23 JUNE 2019 145
