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LONG-TERM MEDICAL OUTCOME
Cardio-vascular risk in ICSI
• HigherbloodpressureinIVF,notinICSIat14y
• Place 2003; Basatemur 2010;Woldringh 2011; Bonduelle 2005; Kai
•
2006; Belva 2007; Knoester 2008
Vascular dysfunction in ART 12y
• •
Scherrer 2012, altered vascular function in ART
Scherrer 2015, Eur Heart J, 2015 review
• ART alters cardiovascular phenotype by epigenetic changes
• ART increases prevalence of prematurity, low birth weight and preeclampsia  conditions known to increase cardiovascular morbidity and mortality in NC
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