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Interventions?
• only few studies
• Lifestyle and weight reduction
• BMI has some effect [OR 1.881.63] (Rowlands et al 2016)
• Lifestyleandimprovementinweighthadpositiveeffectonhealth(Dokrasetal.,2016JCEM)
• OCPS
• Some effect [OR 1.881.62] (Rowlands et al. 2016)
• Aloneorcombinedwithlifestyleimproveshealthandmentaldistress(Dokrasetal.,2016JCEM)
• Metformin and weight reduction
• ImprovementwithMetformin(noplacebogroup)(Hahnetal.,HR2006)
• Antiandrogens?
• No specific treatment has been proven to ameliorate distress substantially in these women (Dokras et al., HR 2018)  Future studies
are needed
Endometrium
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