Page 88 - PCC02
P. 88

 Manipulation
‐ Embryo biopsy ‐
 We assume that biopsy is detrimental at the cleavage stage, but is not at the blastocyst stage
• Why we should be not so adamant about evidence at the blastocyst stage
• The unknowns • Operator
• Biopsytechnique
• Precise stage of biopsy (early/late) • Precise position of biopsy
• Amountofcellsremovedwith respect to the overall number
 Scott et al., 2013
 88
Page 82 of 151
 























































































   86   87   88   89   90