Page 105 - PCC02
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Improving clinical outcome. Faster time to live birth
Relative improvement in birth rate: Time lapse in house algorithm vs standard culture and conventional selection
Retrospective analysis of 23,762 cycles highlights
40% 35% 30% 25% 20% 15% 10%
5% 0%
OR 1.370; 95% Cl 0.763 to 2.450
OR1.19 with 95% CI 1.06 to 1.34
<38 autologous
>37 donor
Fishel et al., RBM Online 2017
27
19%
37%
Future possibilities
Challenges of time lapse now
Handling the large complex data.
Manual or semi automated annotation
Time consuming Subjectivity
Future solutions
Rapid digital imaging
Automatic pattern recognition
Bioinformatics Machine learning
Continuous improvement with progressive modification for embryo selection
E.g. ‘Dana’
E.g. ‘Life Whisperer’
Page 99 of 151
PRECONGRESS COURSE 02 I BARCELONA, SPAIN – 1 JULY 2018 105
Improvement in Live Birth
