Page 104 - PCC02

CARE Fertility simple blastocyst algorithm
Blast 4 ICSI
Blast 4 IVF
var
Min
max
Weight
tSB
0
93.1
2
dB
0
12.5
1
Algorithm classes
KIDr (High= A)
tSB or relSBIVF ≤ 93.1hrs
KIDr tSB or relSBIVF >93.1 hrs (Medium= B) dB ≤ 12.5 hrs
var
Min
max
Weight
relSBIVF
0
93.1
2
dB
0
12.5
1
KIDr (Low= C)
tSB or relSBIVF >93.1 hrs dB >12.5 hrs
A UC
1
0
2 or 3
LB
0.479
0.331
0.146
0.636
Time from insem to SB 93.1h dB 12.5h 2 points 1 point
Algorithm Score
Start of blastulation – simple and effective
Distribution curve of 15,000 embryos
1620 transferred blastocysts with known birth outcome
The distributions are significantly different LB- (red) and LB+ (green)transferred embryo. (M-W U test p< 0.00001).
Monitoring tSB can help select the embryo most likely to result in live birth.
Specific timings may differ according to intrinsic and extrinsic factors.
Unpublished CARE Fertility TLI data
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