Page 99 - Eshre 2018
P. 99
Heterozygous ‐NHEJ Homozygous WT/donor
Injecting CRISP/Cas9 during ICSI to avoid mosaicism in targeting
100% targeting efficiency (58)
Homozygous WT/WT
27%
2%
NHEJ
HDR
71%
The editing mechanism is very unusual...
Page 93 of 130
PRECONGRESS COURSE 01 I BARCELONA, SPAIN – 1 JULY 2018 99
