Page 98 - Eshre 2018

Injection at PN stage
Increase in corrected embryos vs.control But 1 in 4 is mosaic
Some blastomeres still mutantescaped the cut
Injecting CRISP/Cas9 during ICSI to avoids mosaicism in targeting
Development to blastocyst of injected embryos at ICSI is normal
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