Page 129 - Eshre 2018

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Part II: Results
miRNAs
Sertoli-cell-only
Mixed atrophy
Germ cell arrest
Fold change
Corrected P-value
AUC
Fold change
Corrected P-value
AUC
Fold change
Corrected P-value
AUC
hsa-miR-34b*
91.22
0.00236
0.90
58.72
0.00017
0.95
15.79
0.0118
0.85
hsa-miR-34c-5p
73.75
0.00035
0.95
70.39
0.00017
0.99
15.42
0.0127
0.83
hsa-miR-34b
8.87
0.00035
0.95
6.33
0.00017
0.94
6.35
0.0009
0.92
hsa-miR-449a
33.98
0.00238
0.90
32.38
0.00017
0.96
19.44
0.0321
0.78
• Expressed in spermatocytes and round spermatids.
• Down-regulated in patients with NOA and in subfertility.
01.07.2018
Prof. Dr. Eckart Meese Seite
17
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Part II: Conclusion
01.07.2018
Prof. Dr. Eckart Meese Seite
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PRECONGRESS COURSE 01 I BARCELONA, SPAIN – 1 JULY 2018 129