Page 107 - Eshre 2018
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LEARNING OBJECTIVES
1. To understand the requirements of RNA regulation during spermatogenesis.
2. To get familiar with the functions of different types of small non-coding RNAs (miRNAs and piRNAs) in spermatogenesis.
3. To learn about the functions of germline-specific cytoplasmic ribonucleoprotein granules (germ granules) in RNA regulation.
4. To understand the intergenerational role of sperm non-coding RNAs as mediators of paternal epigenetic inheritance.
Spermatogenesis
BIRTH
MEIOSIS I MEIOSIS II
Primordial germ cell
Spermatogonium
Primary Spermatocyte
Secondary Spermatocyte
Round Spermatid (haploid)
Spermatozoon (haploid)
PROLIFERARATION
MEIOSIS
HAPLOID DIFFERENTIAION
mitotic divisions
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