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r‐LH in Poor Ovarian Responders
ESPART
RCT, n=963 POR (Bologna Criteria)
Similar COCs(95% CI −0.47, 0.00) p = 0.054
Lower Biochemical pregnancies OR 0.68 (95% CI 0.49, 0.94) p = 0.020 Similar LBR
post hoc analyses
lower rate of total pregnancy outcome failure
OR 0.52 (95% CI 0.33, 0.82; P = 0.005).
higher live birth rate in patients with moderate and severe POR.
ESPART study 2017
rLH in >35
Bosch et al. 2010
Konig et al. 2013
• (CP) prior cycle
• 75 IU of rFSH substituted by
75 IU of rLH
• from stimulation D1
• Higher implantation rate
• Higher clinical pregnancy rate but not significant
• No OCP
• Added 150IU rLH to r‐FSH
• From stimulation D6
• Similar implantation, pregnancy, miscarriage rate
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