Page 86 - PRECONGRESS COURSE 04
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Vascular receptivity
Spiral arterioles in early secretory phase
Subtle vascular remodelling begins before direct interaction with trophoblast
J Obstet Gynaecol Br Commonw. 1970 Aug;77(8):673‐81. The blood supply of the uterus. 1. Arterial vasculature. Farrer‐Brown G, Beilby JO, Tarbit MH. PMID: 5452128
Decidual spiral artery remodelling begins before cellular interaction with cytotrophoblasts. Craven CM, Morgan T, Ward K. Placenta. 1998 May;19(4):241‐52. PMID: 9639319
In endometrium, inflammatory cells are excluded from arteriolar mural tissue
In early decidua, inflammatory cells colonise and disrupt arteriolar walls before invading trophoblast arrives
uNK (CD56+)
Evidence for immune cell involvement in decidual spiral arteriole remodeling in early human pregnancy. Smith SD, Dunk CE, Aplin JD, Harris LK, Jones RL. Am J Pathol. 2009 May;174(5):1959‐71. PMID: 19349361
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