Page 84 - PRECONGRESS COURSE 04

Endometrial glands
image:
Alan Enders
Secondary villus stage immunostained for cytokeratin. Cytotrophoblast cells invading the endometrium radiate away from the trophoblastic shell towards a group of (CK+) glands. Cytotrophoblasts from the shell invade and plug the mouths of endometrial spiral arterioles, preventing blood from accessing the developing intervillous space
Decidual cells
• Decidual cells evolved as an anti‐inflammatory cell type in an interstitially implanting ancestor with a short gestation time
• Inflammatory capacity has been retained as part of a function‐switching repertoire required to deal with pregnancy failure
The Transcriptomic Evolution of Mammalian Pregnancy: Gene Expression Innovations in Endometrial Stromal Fibroblasts. Kin et al, Genome Biol Evol. 2016 8(8):2459‐73. doi: 10.1093/gbe/evw168. PMID
84