Page 74 - PRECONGRESS COURSE 04
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Selection
• In human many embryos are abnormal, so selection or correction mechanisms are required
Recurrent miscarriage: a defect in nature's quality control?Quenby S, Vince G, Farquharson R, Aplin J. Hum Reprod. 2002;17(8):1959‐63. PMID: 12151421
Chromosome instability is common in human cleavage‐stage embryos. Vanneste et al, Nat Med. 2009;15(5):577‐83. doi: 10.1038/nm.1924. PMID: 19396175
Receptivity: the ability of endometrium to respond to embryonic cells and signals to allow implantation
Embryo selection: the evolutionary drive to minimise maternal investment in nonviable pregnancies
Recurrent miscarriage: a defect in nature's quality control?
Quenby S, Vince G, Farquharson R, Aplin J Hum Reprod. 2002 17:1959‐63.
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