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Indirectness
• How well do the included studies address your review question?
– studies addressing a restricted aspect of your question (PICO)
–indirect comparisons
• compare your eligibility criteria to the
‘Characteristics of included studies’ table
• Generalisability to your target population.
• NOT generalisability to other populations
Is the indirectness...
Not serious serious
Very Serious
...enough that my certainty in the result is
74
71