Page 58 - ESHRE2019

4. Blinding: Outcome assessment +
The outcome of pregnancy was determined at 6 weeks gestation by - confirmation of a gestational sac and heartbeat.
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2 Media A or Media B. The embryologist graded the quality of embryos
“The embryologists randomised the patient to either incubation with
using the standard scale. +
Participants underwent laparoscopy with use of either black or white
dilators intra-operatively. Participants were blind to their allocation. - They were asked to report the amount of discomfort they experienced
the day after the procedure on a 0-10cm scale.
Participants underwent hysterectomy either vaginally or abdominally. 4 They were asked to report the amount of discomfort they experienced
3
the day after the procedure on a 0-10cm scale 5 This was a double blind study.
-? Assessing blinding by outcome
• may reach different conclusions for different outcomes
• measurement of only some outcomes may be blinded
• subjective outcomes may be more vulnerable to bias
e.g. death vs quality of life
• may apply to both performance bias and detection bias
Participants were randomised to either Elonva or daily FSH injections. 6 Participants were asked to rate their satisfaction on a 10 point scale.
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