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• Theyreportsuccessfulreconstitutioninvitrooftheentireprocessofoogenesisfrommousepluripotentstem cells.
• Fullypotentmatureoocytesweregeneratedinculturefromembryonicstemcellsandfrominducedpluripotent stem cells derived from both embryonic fibroblasts and adult tail tipfibroblasts.
• Moreover,pluripotentstemcelllineswerere-derivedfromtheeggsthatweregeneratedinvitro,thereby reconstituting the full female germline cycle in a dish.
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PRECONGRESS COURSE 13 I VIENNA, AUSTRIA – 23 JUNE 2019 49