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3D maturation of hPSCs derived Hepatocytes using the RAFT system.
Trey Gieseck, Plose One 2014
Summary and conclusions
hPSCs can be differentiated into a diversity of cells but understanding human development is essential
3D culture improve maturation and function of hepatocyte like cells but also relevance for toxicology and drug screening
hiPSCs derived hepatocytes can be used to model complex disorders such as NAFLD/NASH
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