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The Yamanaka Experiment
Forced expression of a collection of genes (TFs and others with roles in ES cells) in somatic cells should induce the embryonic stem cell phenotype
24 candidates:
Ecat1, Dpp5, Fbx015, Nanog, ERas,
Dnmt3l, Ecat8, Gdf3, Sox15, Dppa4, Dppa2, Fthl17, Sall4, Oct4, Sox2, Rex1, Utf1, Tcl1, Dppa3, Klf4, b‐cat, cMyc, Stat3, Grb2
8
PRECONGRESS COURSE 13 I VIENNA, AUSTRIA – 23 JUNE 2019 11