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Human plasma / urine proteome and metabolome as valuable sources of biomarkers
Blood is in contact with all internal organs and reflects the consequences of pathophysiological processes throughout the body.
Urine is a result of glomerular filtration, tubular reabsorption and secretion and accumulates changes form the body.
Proteome reflect immediate and characteristic changes in response to disease processses.
Metabolome provides realātime integrative information and defines the molecular phenotype of the organism.
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There are no clinically useful single biomarkers or panels of biomarkers
Rizner T.L.
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