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LEARNING OBJECTIVES
To gain basic knowledge about:
• human proteome and metabolome,
• proteomics and metabolomics in biomarker discovery,
• methodological approaches,
• limitations of proteomic and metabolomic studies in biomarker discovery, • importance of diagnostic algorithms based on omics data.
3
Non‐invasive diagnosis of endometriosis is needed
Endometriosis affects 6% to 10% of reporoductive age women.
There is delay in diagnosis of up to 9 years.
Patients have decreased quality of life due to severe pain and infertility. Endometriosis recurs in 20% to 40% of patients after surgical treatment. Endometriosis is associated with significant economic burden:
‐ 78% of patients lose 5.3 days of work/month,
‐ average total cost of 9579 EUR per woman/year.
Simoens et al. 2012, Rogers et al. 2017 4
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