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Arp2/3 complex
Conserved from yeast to human
Seven stoichiometry subunits
Two actin‐related proteins, Arp2 and Arp3, and five ARPC subunits (ARPC1‐5)
Mullins 1998
Branched actin nucleation by the Arp2/3 complex
actin Arp3
Volkmann et al, Science 2001 Egile et al, PLoS‐Biology 2005 Rouiller et al, JCB, 2008
Arp2
Array treadmilling model in lamellipodia extension
Actin treadmilling in lamellipodia (Mullins lab)
Pollard and Borisy, 2003
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11
Mother filament