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RanGTP gradient as a yardstick for chromatin‐to‐cortex signaling
d2 > d1
No actin induction
d1 > d2
Actin cap induction
Li & Albertini, Nat Rev Mol Cell Bio, 2013
Actin nucleation ‐ formation of actin trimer‐ is the kinetic barrier for actin polymerization.
nucleation
10
PRECONGRESS COURSE 02 I VIENNA, AUSTRIA – 23 JUNE 2019 13