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ESHRE PCC Andrology, Vienna, 2019
Prediction of Miscarriage
All SpermComet parameters are highly predictive
Result parameter
Threshold ROC curve P value Sensitivity Specificity PPV NPV
value
(95% CI)
ACS
>=25%
0.967
(0.923‐0.999)
<0.0001
0.909
0.925
0.769
0.974
LCS HCS
<=78% 0.963 (0.911‐0.999)
>=6% 0.905 (0.819‐0.990)
<0.0001 0.999 0.825 <0.0001 0.864 0.863
0.611 0.999 0.633 0.958
What next?
Source: SpermComet fertile donor database (N= 80); SpermComet Miscarriage (N=122) .
ESHRE PCC Andrology, Vienna, 2019
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PRECONGRESS COURSE 01 I VIENNA, AUSTRIA – 23 JUNE 2019 19