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HEALTH OF ICSI CHILDREN IN THE FUTURE, CAN WE BALANC THE RISKS?
Conclusions
Slightly higher risk, mostly related to parental background
• Neonatal period:
More adverse outcome
More malformations
• Growth,vision,hearing:OK
• Development:OK
• Psycho-social:OK
• Metabolic:slightdifferences
• Reproductiveoutcomes:riskinICSIboys
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HEALTH OF ICSI CHILDREN IN THE FUTURE, CAN WE BALANCE THE RISKS?
Conclusions
Limitations
• ICSI cohort limited number (at adulthood)
• NOA (non obstructive azospermia): limited data
• Transgenerational effect of deficient spermatogenesis?
• Special attention to
Cardio metabolic risk after puberty
Epigenetic syndromes / Cancer risk? Reproductive capacity of ICSI boys, and girls?
Further prospective, large and good quality studies
focus on all these health outcomes i focus adulthood and next generations
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