Page 154 - ESHRE2019

REPRODUCTIVE HEALTH
Reproductive hormones
• Risk for abnomal values in ICSI = SC FSH >90th percentile (5.5 IU/L)
Inhibin B <10th percentile (125.2 ng/L)
24% boys high FSH, compared to 9% in SC
• ICSI boys have more risk for higher FSH
FSH (IU/L)
N with level >90th percentile
Inhibin B (ng/L)
N with level <10th percentile
ICSI N=54
13 (24%)
9 (17%)
SC N=57
5 (9%)
5 (9%)
P
0.04
0.3
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SRTEUPRDODEUSCITGINVEÉTHUEDAELTDHE Analyse du sperme
ICSI N=54
SC N=57
P
Adjusted for covariates
Logistic regression: AOR; 95%CI
P
Concentration <15 million/mL
23 (43%)
12 (21%)
0.01
2.7; 1.1‐6.7
0.03
Concentration <5 million/mL
8 (15%)
4 (7%)
NS
2.6; 0.6‐10.7
0.2
Progressive motility <32%
14 (26%)
5 (9%)
0.02
2.3; 0.7‐7.9
0.1
Normal morphology <4%
Resultats
Total count <39 million
34 (64%)
26 (45%)
0.05
2.3; 0.9‐5.4
0.06
28 (54%)
13 (23%)
0.001
4.3; 1.7‐11.3
0.002
• ICSI boys have 3 x more risk for too low sperm concentration < 15 million/mL
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