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NNT by Testi-ICSI (vs. Ejac-ICSI) to achieve each additional live birth was 4.9 (95% CI 2.8-16.8)
Esteves et al., Fertil Steril 2015
Esteves, 31
507 ICSI cycles
3,840 injected oocytes
Study
Design
Population
No. patients/ cycles
SDF test (cutoff)
ICSI Outcome
Greco 2005
Case-control
ICSI failure (≥2); normozoospermia1
18
TUNEL (15%)
2PN, CPR
Esteves 2015
Prospective
Non-ICSI failure; oligozoospermia
172
SCD (30%)
2PN, CPR, miscarriage,
LBR
Pabuccu 2016
Retrospective
ICSI failure (≥2); normozoospermia
71
TUNEL (30%)
2PN, CPR
Bradley 2016
Retrospective
Non-ICSI failure; oligozoospermia1
228
SCIT2 (29%)
2PN, CPR, miscarriage,
LBR
Esteves, 32
1calculated mean or median sperm concentration; 2Variation of SCSA
Esteves, 32
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PRECONGRESS COURSE 01 I VIENNA, AUSTRIA – 23 JUNE 2019 121
