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• Prospective, observational, cohort study with 172 infertile couples
• First IVF-ICSI cycle
• Mild/moderate idiopathic oligozoospermia (5-15x106/mL)
• Persistently elevated SDF (SCD>30%) after 3-month oral AOX
• No detectable female factors, women <39 years-old
• Main outcome measures: CPR, LBR, miscarriage
• Powered (80%) to detect a 30% difference in LBR between groups
Esteves et al., Fertil Steril 2015
Esteves, 29
Prospective cohort study of testicular vs. ejaculated sperm in men with high SDF undergoing ICSI
Esteves et al., Fertil Steril 2015 Esteves, 30
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